Articles from Stroke

Link to journal online
Moseley, Michael E. PhD
Molecular Imaging and Stroke
Stroke. 40(3) (Supplement 1):S30-S33, March 2009.


Cramer, Steven C. MD
Use of Imaging in Restorative Stroke Trials
Stroke. 40(3) (Supplement 1):S28-S29, March 2009.
Abstract
mdash;: Restorative therapies aim to improve behavioral outcome after stroke by promoting repair and restoration. Measures of CNS injury and function might be useful to evaluate such therapies in a clinical trial, for example, by optimizing patient selection or treatment dose. These issues are considered in this review, with specific examples provided

Soares, Bruno P. MD; Chien, Jeffrey D. BA; Wintermark, Max MD;
MR and CT Monitoring of Recanalization, Reperfusion, and Penumbra Salvage: Everything That Recanalizes Does Not Necessarily Reperfuse!
Stroke. 40(3) (Supplement 1):S24-S27, March 2009.
Abstract
mdash;: Revascularization therapies for acute stroke patients aim to rescue the ischemic penumbra by restoring the patency of the occluded artery ("recanalization") and the downstream capillary blood flow ("reperfusion"). This article reviews the definition of recanalization and reperfusion used in stroke clinical trials and their limitations and proposes a study design to determine the relative importance of recanalization, reperfusion, and collateral flow in evaluating the efficacy of revascularization therapies for acute ischemic stroke.(C) 2009 American Heart Association, Inc.