Interventional Cardiovascular Magnetic Resonance: Still Tantalizing
Ratnayaka K, Faranesh AZ, Guttman MA, Kocaturk O, Saikus CE, Lederman RJ
Journal of Cardiovascular Magnetic Resonance 2008, 10:62 (29 December 2008)
[Abstract] [Provisional PDF]
Friday 2 January 2009
Articles from Stroke
Link to journal online
Toth, Gabor ; Albers, Gregory W.
Use of MRI to Estimate the Therapeutic Window in Acute Stroke: Is Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch an EPITHET for Salvageable Ischemic Brain Tissue?
Source
Stroke. 40(1):333-335, January 2009.
Cai, Weibo ; Guzman, Raphael ; Hsu, Andrew R. ; Wang, Hui ; Chen, Kai et al
Positron Emission Tomography Imaging of Poststroke Angiogenesis
Stroke. 40(1):270-277, January 2009.
Abstract
Background and Purpose-: Vascular endothelial growth factor (VEGF) and VEGF receptors (VEGFRs) play important roles during neurovascular repair after stroke. In this study, we imaged VEGFR expression with positron emission tomography (PET) to noninvasively analyze poststroke angiogenesis.Methods-: Female Sprague-Dawley rats after distal middle cerebral artery occlusion surgery were subjected to weekly MRI, 18F-FDG PET, and 64Cu-DOTA-VEGF121 PET scans. Several control experiments were performed to confirm the VEGFR specificity of 64Cu-DOTA-VEGF121 uptake in the stroke border zone. VEGFR, BrdU, lectin staining, and 125I-VEGF165 autoradiography on stroke brain tissue slices were performed to validate the in vivo findings.Results-: T2-weighed MRI correlated with the "cold spot" on 18F-FDG PET for rats undergoing distal middle cerebral artery occlusion surgery. The 64Cu-DOTA-VEGF121 uptake in the stroke border zone peaked at [almost equal to]10 days after surgery, indicating neovascularization as confirmed by histology (VEGFR-2, BrdU, and lectin staining). VEGFR specificity of 64Cu-DOTA-VEGF121 uptake was confirmed by significantly lower uptake of 64Cu-DOTA-VEGFmutant in vivo and intense 125I-VEGF165 uptake ex vivo in the stroke border zone. No appreciable uptake of 64Cu-DOTA-VEGF121 was observed in the brain of sham-operated rats.Conclusions-: For the first time to our knowledge, we successfully evaluated the VEGFR expression kinetics noninvasively in a rat stroke model. In vivo imaging of VEGFR expression could become a significant clinical tool to plan and monitor therapies aimed at improving poststroke angiogenesis.
Izquierdo-Garcia, David ; Davies, John R. ; Graves, Martin J. et al
Comparison of Methods for Magnetic Resonance-Guided [18-F]Fluorodeoxyglucose Positron Emission Tomography in Human Carotid Arteries: Reproducibility, Partial Volume Correction, and Correlation Between Methods.
Stroke. 40(1):86-93, January 2009.
Abstract
Background and Purpose-: Inflammation is a major risk factor for atherosclerotic plaque rupture and clinical events. Previous studies have shown that plaque [18F]fluorodeoxyglucose (FDG) uptake correlates with macrophage content. In this study we examined the reproducibility of 3 methods of quantifying plaque FDG uptake in the carotid arteries using positron emission tomography (PET). The correlation between 2 simplified uptake parameters (standardized uptake value [SUV], vessel wall-to-blood ratio [VBR]) and a gold standard technique (influx rate [Ki]) was also determined. We used MRI to correct carotid plaque FDG uptake for partial volume error.Methods-: Seven patients with a recent carotid territory transient ischemic attack underwent imaging twice within 8 days using MR and FDG-PET. MR coregistered to PET was used to delineate regions of interest, and to facilitate partial volume correction (PVC).Results-: SUV was the most reproducible parameter irrespective of whether it was normalized by body surface area (BSA), lean body mass, or weight (intraclass correlation coefficient=0.85, 0.88, and 0.90, respectively). VBR correlated better to Ki than SUV (r=0.58 VBR, r=0.46 SUVBSA). PVC improved these correlations to r=0.81 VBR and r=0.76 SUVBSA, and only slightly degraded the reproducibility of SUV (intraclass correlation coefficient=0.83-0.85).Conclusions-: MR-guided FDG-PET is a highly reproducible technique in the carotid artery and the excellent anatomic detail provided by MR facilitates PVC. Of the methods examined, SUVBSAPVC appears to represent the best compromise between reproducible and accurate determination of FDG metabolism in carotid artery vessel wall.
Toth, Gabor ; Albers, Gregory W.
Use of MRI to Estimate the Therapeutic Window in Acute Stroke: Is Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch an EPITHET for Salvageable Ischemic Brain Tissue?
Source
Stroke. 40(1):333-335, January 2009.
Cai, Weibo ; Guzman, Raphael ; Hsu, Andrew R. ; Wang, Hui ; Chen, Kai et al
Positron Emission Tomography Imaging of Poststroke Angiogenesis
Stroke. 40(1):270-277, January 2009.
Abstract
Background and Purpose-: Vascular endothelial growth factor (VEGF) and VEGF receptors (VEGFRs) play important roles during neurovascular repair after stroke. In this study, we imaged VEGFR expression with positron emission tomography (PET) to noninvasively analyze poststroke angiogenesis.Methods-: Female Sprague-Dawley rats after distal middle cerebral artery occlusion surgery were subjected to weekly MRI, 18F-FDG PET, and 64Cu-DOTA-VEGF121 PET scans. Several control experiments were performed to confirm the VEGFR specificity of 64Cu-DOTA-VEGF121 uptake in the stroke border zone. VEGFR, BrdU, lectin staining, and 125I-VEGF165 autoradiography on stroke brain tissue slices were performed to validate the in vivo findings.Results-: T2-weighed MRI correlated with the "cold spot" on 18F-FDG PET for rats undergoing distal middle cerebral artery occlusion surgery. The 64Cu-DOTA-VEGF121 uptake in the stroke border zone peaked at [almost equal to]10 days after surgery, indicating neovascularization as confirmed by histology (VEGFR-2, BrdU, and lectin staining). VEGFR specificity of 64Cu-DOTA-VEGF121 uptake was confirmed by significantly lower uptake of 64Cu-DOTA-VEGFmutant in vivo and intense 125I-VEGF165 uptake ex vivo in the stroke border zone. No appreciable uptake of 64Cu-DOTA-VEGF121 was observed in the brain of sham-operated rats.Conclusions-: For the first time to our knowledge, we successfully evaluated the VEGFR expression kinetics noninvasively in a rat stroke model. In vivo imaging of VEGFR expression could become a significant clinical tool to plan and monitor therapies aimed at improving poststroke angiogenesis.
Izquierdo-Garcia, David ; Davies, John R. ; Graves, Martin J. et al
Comparison of Methods for Magnetic Resonance-Guided [18-F]Fluorodeoxyglucose Positron Emission Tomography in Human Carotid Arteries: Reproducibility, Partial Volume Correction, and Correlation Between Methods.
Stroke. 40(1):86-93, January 2009.
Abstract
Background and Purpose-: Inflammation is a major risk factor for atherosclerotic plaque rupture and clinical events. Previous studies have shown that plaque [18F]fluorodeoxyglucose (FDG) uptake correlates with macrophage content. In this study we examined the reproducibility of 3 methods of quantifying plaque FDG uptake in the carotid arteries using positron emission tomography (PET). The correlation between 2 simplified uptake parameters (standardized uptake value [SUV], vessel wall-to-blood ratio [VBR]) and a gold standard technique (influx rate [Ki]) was also determined. We used MRI to correct carotid plaque FDG uptake for partial volume error.Methods-: Seven patients with a recent carotid territory transient ischemic attack underwent imaging twice within 8 days using MR and FDG-PET. MR coregistered to PET was used to delineate regions of interest, and to facilitate partial volume correction (PVC).Results-: SUV was the most reproducible parameter irrespective of whether it was normalized by body surface area (BSA), lean body mass, or weight (intraclass correlation coefficient=0.85, 0.88, and 0.90, respectively). VBR correlated better to Ki than SUV (r=0.58 VBR, r=0.46 SUVBSA). PVC improved these correlations to r=0.81 VBR and r=0.76 SUVBSA, and only slightly degraded the reproducibility of SUV (intraclass correlation coefficient=0.83-0.85).Conclusions-: MR-guided FDG-PET is a highly reproducible technique in the carotid artery and the excellent anatomic detail provided by MR facilitates PVC. Of the methods examined, SUVBSAPVC appears to represent the best compromise between reproducible and accurate determination of FDG metabolism in carotid artery vessel wall.
Articles from Anesthesia and Analgesia
Link to journal online
Dzwonczyk, Roger; Fujii, Jeffrey T. ; Simonetti, Orlando ; Nieves-Ramos, Ricardo ; Bergese, Sergio D.
Electrical Noise in the Intraoperative Magnetic Resonance Imaging Setting
Anesthesia & Analgesia. 108(1):181-186, January 2009.
Abstract
BACKGROUND: Intraoperative magnetic resonance imaging (iMRI) is a tool now commonly used in neurosurgery. Safe and reliable patient care in this (or any other) operating room setting depends on an environment, where electrical noise (EN) does not interfere with the operation of the electronic monitoring or imaging equipment. In this investigation, we evaluated the EN generated by the iMRI system and the anesthesia patient monitor used at this institution that impacts the performance of these two devices.METHODS: We measured the EN generated by our iMRI-compatible anesthesia patient monitor as detected by the EN analysis algorithm in our iMRI system. We measured the EN generated by our iMRI system during scanning as detected in the electrocardiogram (ECG) waveform of our patient monitor. We analyzed the effects on EN reduction and signal quality of the ECG noise filters provided in our iMRI-compatible anesthesia patient monitor.RESULTS: Our patient monitor generated EN that was detectable by the iMRI EN analysis algorithm; however, this interference was within the iMRI manufacturer's acceptable limits for an iMRI scan (<10%>
Kronzon, Itzhak MD
Dzwonczyk, Roger; Fujii, Jeffrey T. ; Simonetti, Orlando ; Nieves-Ramos, Ricardo ; Bergese, Sergio D.
Electrical Noise in the Intraoperative Magnetic Resonance Imaging Setting
Anesthesia & Analgesia. 108(1):181-186, January 2009.
Abstract
BACKGROUND: Intraoperative magnetic resonance imaging (iMRI) is a tool now commonly used in neurosurgery. Safe and reliable patient care in this (or any other) operating room setting depends on an environment, where electrical noise (EN) does not interfere with the operation of the electronic monitoring or imaging equipment. In this investigation, we evaluated the EN generated by the iMRI system and the anesthesia patient monitor used at this institution that impacts the performance of these two devices.METHODS: We measured the EN generated by our iMRI-compatible anesthesia patient monitor as detected by the EN analysis algorithm in our iMRI system. We measured the EN generated by our iMRI system during scanning as detected in the electrocardiogram (ECG) waveform of our patient monitor. We analyzed the effects on EN reduction and signal quality of the ECG noise filters provided in our iMRI-compatible anesthesia patient monitor.RESULTS: Our patient monitor generated EN that was detectable by the iMRI EN analysis algorithm; however, this interference was within the iMRI manufacturer's acceptable limits for an iMRI scan (<10%>
Skubas, Nikolaos
Intraoperative Doppler Tissue Imaging Is a Valuable Addition to Cardiac Anesthesiologists' Armamentarium: A Core Review. [Review]
Anesthesia & Analgesia. 108(1):48-66, January 2009.
Abstract
Endocardial motion and surface/volume changes during the cardiac cycle are echocardiographic methods for regional (analysis of wall motion) and global (fractional area change, stroke volume, and ejection fraction) evaluation of cardiac function. These conventional methods can be subjective, and/or time consuming and, depending upon circumstances, may divert the anesthesiologist's attention from intraoperative activities. Doppler tissue imaging (DTI) is a novel echocardiographic technique, which displays and measures systolic and diastolic velocity from a myocardial region. DTI is simple to perform and independent of adequate endocardial imaging. The numeric information (velocity or time intervals) is easily obtained and measured. Assessment of systolic and diastolic function on regional (detection of ischemia) as well as global level (ejection fraction, grading of diastolic dysfunction) and evaluation of filling pressure can be derived from DTI signals and used by any practicing cardiac anesthesiologist. This review describes the principles, imaging modalities, and clinical applications of DTI.(C) 2009 by International Anesthesia Research Society.
Anesthesia & Analgesia. 108(1):48-66, January 2009.
Abstract
Endocardial motion and surface/volume changes during the cardiac cycle are echocardiographic methods for regional (analysis of wall motion) and global (fractional area change, stroke volume, and ejection fraction) evaluation of cardiac function. These conventional methods can be subjective, and/or time consuming and, depending upon circumstances, may divert the anesthesiologist's attention from intraoperative activities. Doppler tissue imaging (DTI) is a novel echocardiographic technique, which displays and measures systolic and diastolic velocity from a myocardial region. DTI is simple to perform and independent of adequate endocardial imaging. The numeric information (velocity or time intervals) is easily obtained and measured. Assessment of systolic and diastolic function on regional (detection of ischemia) as well as global level (ejection fraction, grading of diastolic dysfunction) and evaluation of filling pressure can be derived from DTI signals and used by any practicing cardiac anesthesiologist. This review describes the principles, imaging modalities, and clinical applications of DTI.(C) 2009 by International Anesthesia Research Society.
Tousignant, Claude
CON: Intraoperative Doppler Tissue Imaging Is a Valuable Addition to Cardiac Anesthesiologists' Armamentarium. [Editorial]
Source
Anesthesia & Analgesia. 108(1):41-47, January 2009.
CON: Intraoperative Doppler Tissue Imaging Is a Valuable Addition to Cardiac Anesthesiologists' Armamentarium. [Editorial]
Source
Anesthesia & Analgesia. 108(1):41-47, January 2009.
Kronzon, Itzhak MD
PRO: Intraoperative Doppler Tissue Imaging Is a Valuable Addition to Cardiac Anesthesiologists' Armamentarium. [Editorial]
Source
Anesthesia & Analgesia. 108(1):37-40, January 2009.
Source
Anesthesia & Analgesia. 108(1):37-40, January 2009.
Hilberath, Jan N. ; Shernan, Stanton K. ; Segal, Scott ; Smith, Brian et al
The Feasibility of Epicardial Echocardiography for Measuring Aortic Valve Area by the Continuity Equation
Anesthesia & Analgesia. 108(1):17-22, January 2009.
Abstract
BACKGROUND: Measuring the aortic valve area (AVA) remains an important component of a comprehensive intraoperative echocardiographic examination in patients undergoing aortic valve surgery. Epicardial echocardiography (EE) represents an accessible alternative to transesophageal echocardiography (TEE), however, its agreement and correlation with other imaging modalities for measuring AVA has not been systematically validated.METHODS: EE was used in 85 patients undergoing cardiac surgery to measure AVA (AVA-EE) using the continuity equation. AVA-EE was compared to measurements obtained by intraoperative transesophageal echocardiography (AVA-TEE) in the same population. In a subset of patients, AVA-EE was also compared to AVA measurements from either preoperative transthoracic echocardiography (AVA-TTE) (n = 65) or cardiac catheterization (AVA-Cath) (n = 35) that were acquired within 4 wk before the date of surgery.RESULTS: Adequate trans-AV Doppler recordings were obtained in 94% of patients for AVA-TEE and 100% of patients for AVA-EE. EE measurements of AVA showed close agreement with TEE measurements (mean difference [bias] +/- 95% CI = -0.09 cm2 +/- 0.18 cm2, r2 = 0.83, P < ci =" -0.03" r2 =" 0.87," ci =" -0.06" r2 =" 0.81,">
Abstract
BACKGROUND: Measuring the aortic valve area (AVA) remains an important component of a comprehensive intraoperative echocardiographic examination in patients undergoing aortic valve surgery. Epicardial echocardiography (EE) represents an accessible alternative to transesophageal echocardiography (TEE), however, its agreement and correlation with other imaging modalities for measuring AVA has not been systematically validated.METHODS: EE was used in 85 patients undergoing cardiac surgery to measure AVA (AVA-EE) using the continuity equation. AVA-EE was compared to measurements obtained by intraoperative transesophageal echocardiography (AVA-TEE) in the same population. In a subset of patients, AVA-EE was also compared to AVA measurements from either preoperative transthoracic echocardiography (AVA-TTE) (n = 65) or cardiac catheterization (AVA-Cath) (n = 35) that were acquired within 4 wk before the date of surgery.RESULTS: Adequate trans-AV Doppler recordings were obtained in 94% of patients for AVA-TEE and 100% of patients for AVA-EE. EE measurements of AVA showed close agreement with TEE measurements (mean difference [bias] +/- 95% CI = -0.09 cm2 +/- 0.18 cm2, r2 = 0.83, P < ci =" -0.03" r2 =" 0.87," ci =" -0.06" r2 =" 0.81,">
AJR Vol 192 No1 January 2009
Editor's Notebook
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Online Versus Print: Responses Galore!
Thomas H. Berquist
AJR 2009;192:1-2
http://www.ajronline.org/cgi/content/full/192/1/1
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Special Articles
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Evaluation of a Single-Pass Continuous Whole-Body 16-MDCT Protocol for
Patients with Polytrauma
Duy Nguyen, Alexandra Platon, Kathirkamanathan Shanmuganathan, Stuart
E. Mirvis, Christoph D. Becker, and Pierre-Alexandre Poletti
AJR 2009;192:3-10
http://www.ajronline.org/cgi/content/abstract/192/1/3
Color Comet-Tail Artifact: Clinical Applications
Hisham Tchelepi and Philip W. Ralls
AJR 2009;192:11-18
http://www.ajronline.org/cgi/content/abstract/192/1/11
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Cardiopulmonary Imaging
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Traditional Clinical Risk Assessment Tools Do Not Accurately Predict
Coronary Atherosclerotic Plaque Burden: A CT Angiography Study
Kevin M. Johnson, David A. Dowe, and James A. Brink
AJR 2009;192:235-243
http://www.ajronline.org/cgi/content/abstract/192/1/235
Radiation Dose Savings for Adult Pulmonary Embolus 64-MDCT Using Bismuth
Breast Shields, Lower Peak Kilovoltage, and Automatic Tube Current
Modulation
Lynne M. Hurwitz, Terry T. Yoshizumi, Philip C. Goodman, Rendon C.
Nelson, Greta Toncheva, Giao B. Nguyen, Carolyn Lowry, and Colin
Anderson-Evans
AJR 2009;192:244-253
http://www.ajronline.org/cgi/content/abstract/192/1/244
Acute Myocarditis: Noninvasive Evaluation with Cardiac MRI and
Transthoracic Echocardiography
Orly Goitein, Shlomi Matetzky, Roy Beinart, Elio Di Segni, Hanoch Hod,
Ariel Bentancur, and Eli Konen
AJR 2009;192:254-258
http://www.ajronline.org/cgi/content/abstract/192/1/254
Cardiac MRI and Pulmonary MR Angiography of Sinus Venosus Defect and
Partial Anomalous Pulmonary Venous Connection in Cause of Right Undiagnosed
Ventricular Enlargement
Henryk Kafka and Raad H. Mohiaddin
AJR 2009;192:259-266
http://www.ajronline.org/cgi/content/abstract/192/1/259
Quantitative CT in Chronic Obstructive Pulmonary Disease: Inspiratory and
Expiratory Assessment
Masanori Akira, Kazushige Toyokawa, Yoshikazu Inoue, and Toru Arai
AJR 2009;192:267-272
http://www.ajronline.org/cgi/content/abstract/192/1/267
Cone-Beam Technique for 64-MDCT of Lung: Image Quality Comparison with
Stepwise (Step-and-Shoot) Technique
Yoshinori Funama, Kazuo Awai, Katsuyuki Taguchi, Masahiro Hatemura,
Yumi Yanaga, Masamichi Shimamura, and Yasuyuki Yamashita
AJR 2009;192:273-278
http://www.ajronline.org/cgi/content/abstract/192/1/273
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Gastrointestinal Imaging
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Recurrent Pyogenic Cholangitis: From Imaging to Intervention
Eric J. Heffernan, Tony Geoghegan, Peter L. Munk, Stephen G. Ho, and
Alison C. Harris
AJR 2009;192:28-35
http://www.ajronline.org/cgi/content/abstract/192/1/W28
Is Gadolinium Necessary for MRI Follow-Up Evaluation of Cystic Lesions in
the Pancreas? Preliminary Results
Michael Macari, Terrence Lee, Sooah Kim, Stacy Jacobs, Alec J.
Megibow, Cristina Hajdu, and James Babb
AJR 2009;192:159-164
http://www.ajronline.org/cgi/content/abstract/192/1/159
Three-Dimensional Contrast-Enhanced Sonography of Vascular Patterns of
Focal Liver Tumors: Pilot Study of Visualization Methods
Wen Luo, Kazushi Numata, Manabu Morimoto, Akito Nozaki, Yasuhiko
Nagano, Kazuya Sugimori, and Katsuaki Tanaka
AJR 2009;192:165-173
http://www.ajronline.org/cgi/content/abstract/192/1/165
Sonography of Acute Right Lower Quadrant Pain: Importance of Increased
Intraabdominal Fat Echo
Min Woo Lee, Young Jun Kim, Hae Jeong Jeon, Sang Woo Park, Sung Il
Jung, and Jeong Geun Yi
AJR 2009;192:174-179
http://www.ajronline.org/cgi/content/abstract/192/1/174
Detection of Hepatocellular Carcinoma in Patients with Cirrhosis: Added
Value of Coronal Reformations from Isotropic Voxels with 64-MDCT
Daniele Marin, Carlo Catalano, Gianmaria De Filippis, Michele Di
Martino, Antonino Guerrisi, Massimo Rossi, and Roberto Passariello
AJR 2009;192:180-187
http://www.ajronline.org/cgi/content/abstract/192/1/180
Cross-Sectional Imaging of Acute and Chronic Gallbladder Inflammatory
Disease
Ethan A. Smith, Jonathan R. Dillman, Khaled M. Elsayes, Christine O.
Menias, and Ronald O. Bude
AJR 2009;192:188-196
http://www.ajronline.org/cgi/content/abstract/192/1/188
Transabdominal Sonography in Assessment of the Bowel in Adults
Siarhei Kuzmich, David C. Howlett, Allan Andi, Dhiren Shah, and
Tatsiana Kuzmich
AJR 2009;192:197-212
http://www.ajronline.org/cgi/content/abstract/192/1/197
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Genitourinary Imaging
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MDCT of the Ovarian Vein: Normal Anatomy and Pathology
Devrim Karaosmanoglu, Musturay Karcaaltincaba, Deniz Karcaaltincaba,
Deniz Akata, and Mustafa Ozmen
AJR 2009;192:295-299
http://www.ajronline.org/cgi/content/abstract/192/1/295
Adrenal Pheochromocytoma with Surrounding Brown Fat Stimulation
Revathy B. Iyer, Charles C. Guo, and Nancy Perrier
AJR 2009;192:300-301
http://www.ajronline.org/cgi/content/full/192/1/300
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Women's Imaging
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Timed Efficiency of Interpretation of Digital and Film-Screen Screening
Mammograms
Tamara Miner Haygood, Jihong Wang, E. Neely Atkinson, Deanna Lane,
Tanya W. Stephens, Parul Patel, and Gary J. Whitman
AJR 2009;192:216-220
http://www.ajronline.org/cgi/content/abstract/192/1/216
Sonographic Surveillance for the Detection of Contralateral Metachronous
Breast Cancer in an Asian Population
Min Jung Kim, Eun-Kyung Kim, Jin Young Kwak, Byeong-Woo Park, Seung-Il
Kim, Joohyuk Sohn, and Ki Keun Oh
AJR 2009;192:221-228
http://www.ajronline.org/cgi/content/abstract/192/1/221
Frequency and Upgrade Rates of Atypical Ductal Hyperplasia Diagnosed at
Stereotactic Vacuum-Assisted Breast Biopsy: 9-Versus 11-Gauge
Peter R. Eby, Jennifer E. Ochsner, Wendy B. DeMartini, Kimberly H.
Allison, Sue Peacock, and Constance D. Lehman
AJR 2009;192:229-234
http://www.ajronline.org/cgi/content/abstract/192/1/229
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Musculoskeletal Imaging
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Periosteal Chondrosarcoma
Skander Chaabane, Mouna Chelli Bouaziz, Cyrine Drissi, Leila Abid, and
Mohamed Fethi Ladeb
AJR 2009;192:1-6
http://www.ajronline.org/cgi/content/abstract/192/1/W1
MRI of Isolated Distal Fibular Fractures with Widened Medial Clear Space on
Stressed Radiographs: Which Ligaments Are Interrupted?
Yvonne Cheung, Kiley D. Perrich, Jiang Gui, Kenneth J. Koval, and
Douglas W. Goodwin
AJR 2009;192:7-12
http://www.ajronline.org/cgi/content/abstract/192/1/W7
Imaging the Ligaments of the Trapeziometacarpal Joint: MRI Compared with MR
Arthrography in Cadaveric Specimens
Fabiano Nassar Cardoso, Hyun-Jin Kim, Flavio Albertotti, Michael J.
Botte, Donald Resnick, and Christine B. Chung
AJR 2009;192:13-19
http://www.ajronline.org/cgi/content/abstract/192/1/W13
Normal Sonographic Anatomy of the Posterolateral Corner of the Knee
Robert P. Barker, Justin C. Lee, and Jeremiah C. Healy
AJR 2009;192:73-79
http://www.ajronline.org/cgi/content/abstract/192/1/73
Comparison of 3-T MRI and Arthroscopy of Intrinsic Wrist Ligament and TFCC
Tears
Thomas Magee
AJR 2009;192:80-85
http://www.ajronline.org/cgi/content/abstract/192/1/80
3-T MRI of the Shoulder: Is MR Arthrography Necessary?
Thomas Magee
AJR 2009;192:86-92
http://www.ajronline.org/cgi/content/abstract/192/1/86
MRI Appearance of the Pectinofoveal Fold
Donna G. Blankenbaker, Kirkland W. Davis, Arthur A. De Smet, and James
S. Keene
AJR 2009;192:93-95
http://www.ajronline.org/cgi/content/abstract/192/1/93
Diagnostic Utility of T1-Weighted MRI Characteristics in Evaluation of
Osteomyelitis of the Foot
Paul W. Johnson, Mark S. Collins, and Doris E. Wenger
AJR 2009;192:96-100
http://www.ajronline.org/cgi/content/abstract/192/1/96
Knee Dislocation in Overweight Patients
Erno K. Peltola, Jan Lindahl, Harri Hietaranta, and Seppo K. Koskinen
AJR 2009;192:101-106
http://www.ajronline.org/cgi/content/abstract/192/1/101
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Pediatric Imaging
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CT with a Computer-Simulated Dose Reduction Technique for Detection of
Pediatric Nephroureterolithiasis: Comparison of Standard and Reduced
Radiation Doses
Boaz Karmazyn, Donald P. Frush, Kimberly E. Applegate, Charles
Maxfield, Mervyn D. Cohen, and Robert P. Jones
AJR 2009;192:143-149
http://www.ajronline.org/cgi/content/abstract/192/1/143
MDCT with Coronal Reconstruction: Clinical Benefit in Evaluation of
Suspected Acute Appendicitis in Pediatric Patients
Yoo Jin Kim, Jee-Eun Kim, Hyung Sik Kim, and Hee Young Hwang
AJR 2009;192:150-152
http://www.ajronline.org/cgi/content/abstract/192/1/150
Congenital Diaphragmatic Hernia: Predictive Value of MRI Relative
Lung-to-Head Ratio Compared with MRI Fetal Lung Volume and Sonographic
Lung-to-Head Ratio
A. Kristina Kilian, Thomas Schaible, Valeska Hofmann, Joachim Brade,
K. Wolfgang Neff, and Karen A. Busing
AJR 2009;192:153-158
http://www.ajronline.org/cgi/content/abstract/192/1/153
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Vascular and Interventional Radiology
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MDCT Angiography After Open Thoracic Aortic Surgery: Pearls and Pitfalls
Jenny K. Hoang, Santiago Martinez, and Lynne M. Hurwitz
AJR 2009;192:20-27
http://www.ajronline.org/cgi/content/abstract/192/1/W20
CT-Guided Percutaneous Catheter Drainage of Acute Necrotizing Pancreatitis:
Clinical Experience and Observations in Patients with Sterile and Infected
Necrosis
Koenraad J. Mortele, Jeffrey Girshman, Denis Szejnfeld, Stanley W.
Ashley, Sukru M. Erturk, Peter A. Banks, and Stuart G. Silverman
AJR 2009;192:110-116
http://www.ajronline.org/cgi/content/abstract/192/1/110
Diagnostic Accuracy of Intraarterial and IV MR Angiography for the
Detection of Stenoses of the Infrainguinal Arteries
Florian Poschenrieder, Okka W. Hamer, Thomas Herold, Thomas
Schleicher, Ingitha Borisch, Stefan Feuerbach, and Niels Zorger
AJR 2009;192:117-121
http://www.ajronline.org/cgi/content/abstract/192/1/117
Evaluation of Patients with Esophageal Varices After Endoscopic Injection
Sclerotherapy Using Multiplanar Reconstruction MDCT Images
Hideaki Kodama, Hiroshi Aikata, Shintaro Takaki, Shoichi Takahashi,
Naoyuki Toyota, Katsuhide Ito, and Kazuaki Chayama
AJR 2009;192:122-130
http://www.ajronline.org/cgi/content/abstract/192/1/122
Predictive Value of Percutaneous Imaging-Guided Biopsy of Peritoneal and
Omental Masses: Results in 111 Patients
Frederico F. Souza, Koenraad J. Mortele, Edmund S. Cibas, Sukru M.
Erturk, and Stuart G. Silverman
AJR 2009;192:131-136
http://www.ajronline.org/cgi/content/abstract/192/1/131
CT-Guided Radiofrequency Ablation in the Treatment of Recurrent Rectal
Cancer
Giuseppe Belfiore, Enrico Tedeschi, Francesco Michele Ronza, Maria
Paola Belfiore, Ettore Borsi, Giovanni Pietro Ianniello, and Antonio
Rotondo
AJR 2009;192:137-141
http://www.ajronline.org/cgi/content/abstract/192/1/137
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Letter
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Intermetatarsal Fat Pad Sign: Radiographic Aid to Diagnosis of Occult
Tarsometatarsal Joint Injuries
Vincent Timpone, Michael Tall, and Andrew Puckett
AJR 2009;192:36-37
http://www.ajronline.org/cgi/content/full/192/1/W36
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Book Reviews
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Imaging of the Chest, vols. 1 and II
Howard I. Jolles
AJR 2009;192:38
http://www.ajronline.org/cgi/content/full/192/1/W38
Keats & Kahn's Roentgen Atlas of Skeletal Maturation
Lane F. Donnelly
AJR 2009;192:39
http://www.ajronline.org/cgi/content/full/192/1/W39
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Nuclear Medicine and Molecular Imaging
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Quantitative Molecular Imaging of Viral Therapy for Pancreatic Cancer Using
an Engineered Measles Virus Expressing the Sodium-Iodide Symporter Reporter
Gene
Stephanie K. Carlson, Kelly L. Classic, Elizabeth M. Hadac, David
Dingli, Claire E. Bender, Bradley J. Kemp, and Stephen J. Russell
AJR 2009;192:279-287
http://www.ajronline.org/cgi/content/abstract/192/1/279
Spectrum of 18F-FDG PET/CT Findings in Oncology-Related Recurrent Laryngeal
Nerve Palsy
Maria Komissarova, Ka Kit Wong, Morand Piert, Suresh K. Mukherji, and
Lorraine M. Fig
AJR 2009;192:288-294
http://www.ajronline.org/cgi/content/abstract/192/1/288
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Neuroradiology/Head and Neck Imaging
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Advances in Pediatric Neuroradiology: Highlights of the Recent Medical
Literature
James M. Provenzale
AJR 2009;192:19-25
http://www.ajronline.org/cgi/content/abstract/192/1/19
Evaluation of the Pediatric Craniocervical Junction on MDCT
John Christopher Bertozzi, Carlos Andres Rojas, and Carlos Rodrigo
Martinez
AJR 2009;192:26-31
http://www.ajronline.org/cgi/content/abstract/192/1/26
Spectrum of Choroid Plexus Lesions in Children
Ramin M. Naeini, Jeong Hyun Yoo, and Jill V. Hunter
AJR 2009;192:32-40
http://www.ajronline.org/cgi/content/abstract/192/1/32
Imaging Findings in Neonatal Hypoxia: A Practical Review
E. Ralph Heinz and James M. Provenzale
AJR 2009;192:41-47
http://www.ajronline.org/cgi/content/abstract/192/1/41
Brain and Bone Abnormalities of Thanatophoric Dwarfism
Elka Miller, Susan Blaser, Patrick Shannon, and Elysa Widjaja
AJR 2009;192:48-51
http://www.ajronline.org/cgi/content/abstract/192/1/48
Diagnostic Determinants of Craniocervical Distraction Injury in Adults
Wilbur Chang, Melvin T. Alexander, and Stuart E. Mirvis
AJR 2009;192:52-58
http://www.ajronline.org/cgi/content/abstract/192/1/52
Correlation of Neurodevelopmental Features and MRI Findings in Infantile
Krabbe's Disease
James M. Provenzale, Srinivas Peddi, Joanne Kurtzberg, Michele D. Poe,
Srinivasan Mukundan, and Maria Escolar
AJR 2009;192:59-65
http://www.ajronline.org/cgi/content/abstract/192/1/59
Performance of Preoperative Sonographic Staging of Papillary Thyroid
Carcinoma Based on the Sixth Edition of the AJCC/UICC TNM Classification
System
Jeong Seon Park, Kyu-Ri Son, Dong Gyu Na, Eunhee Kim, and Sungjun Kim
AJR 2009;192:66-72
http://www.ajronline.org/cgi/content/abstract/192/1/66
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Online Versus Print: Responses Galore!
Thomas H. Berquist
AJR 2009;192:1-2
http://www.ajronline.org/cgi/content/full/192/1/1
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Special Articles
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Evaluation of a Single-Pass Continuous Whole-Body 16-MDCT Protocol for
Patients with Polytrauma
Duy Nguyen, Alexandra Platon, Kathirkamanathan Shanmuganathan, Stuart
E. Mirvis, Christoph D. Becker, and Pierre-Alexandre Poletti
AJR 2009;192:3-10
http://www.ajronline.org/cgi/content/abstract/192/1/3
Color Comet-Tail Artifact: Clinical Applications
Hisham Tchelepi and Philip W. Ralls
AJR 2009;192:11-18
http://www.ajronline.org/cgi/content/abstract/192/1/11
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Cardiopulmonary Imaging
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Traditional Clinical Risk Assessment Tools Do Not Accurately Predict
Coronary Atherosclerotic Plaque Burden: A CT Angiography Study
Kevin M. Johnson, David A. Dowe, and James A. Brink
AJR 2009;192:235-243
http://www.ajronline.org/cgi/content/abstract/192/1/235
Radiation Dose Savings for Adult Pulmonary Embolus 64-MDCT Using Bismuth
Breast Shields, Lower Peak Kilovoltage, and Automatic Tube Current
Modulation
Lynne M. Hurwitz, Terry T. Yoshizumi, Philip C. Goodman, Rendon C.
Nelson, Greta Toncheva, Giao B. Nguyen, Carolyn Lowry, and Colin
Anderson-Evans
AJR 2009;192:244-253
http://www.ajronline.org/cgi/content/abstract/192/1/244
Acute Myocarditis: Noninvasive Evaluation with Cardiac MRI and
Transthoracic Echocardiography
Orly Goitein, Shlomi Matetzky, Roy Beinart, Elio Di Segni, Hanoch Hod,
Ariel Bentancur, and Eli Konen
AJR 2009;192:254-258
http://www.ajronline.org/cgi/content/abstract/192/1/254
Cardiac MRI and Pulmonary MR Angiography of Sinus Venosus Defect and
Partial Anomalous Pulmonary Venous Connection in Cause of Right Undiagnosed
Ventricular Enlargement
Henryk Kafka and Raad H. Mohiaddin
AJR 2009;192:259-266
http://www.ajronline.org/cgi/content/abstract/192/1/259
Quantitative CT in Chronic Obstructive Pulmonary Disease: Inspiratory and
Expiratory Assessment
Masanori Akira, Kazushige Toyokawa, Yoshikazu Inoue, and Toru Arai
AJR 2009;192:267-272
http://www.ajronline.org/cgi/content/abstract/192/1/267
Cone-Beam Technique for 64-MDCT of Lung: Image Quality Comparison with
Stepwise (Step-and-Shoot) Technique
Yoshinori Funama, Kazuo Awai, Katsuyuki Taguchi, Masahiro Hatemura,
Yumi Yanaga, Masamichi Shimamura, and Yasuyuki Yamashita
AJR 2009;192:273-278
http://www.ajronline.org/cgi/content/abstract/192/1/273
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Gastrointestinal Imaging
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Recurrent Pyogenic Cholangitis: From Imaging to Intervention
Eric J. Heffernan, Tony Geoghegan, Peter L. Munk, Stephen G. Ho, and
Alison C. Harris
AJR 2009;192:28-35
http://www.ajronline.org/cgi/content/abstract/192/1/W28
Is Gadolinium Necessary for MRI Follow-Up Evaluation of Cystic Lesions in
the Pancreas? Preliminary Results
Michael Macari, Terrence Lee, Sooah Kim, Stacy Jacobs, Alec J.
Megibow, Cristina Hajdu, and James Babb
AJR 2009;192:159-164
http://www.ajronline.org/cgi/content/abstract/192/1/159
Three-Dimensional Contrast-Enhanced Sonography of Vascular Patterns of
Focal Liver Tumors: Pilot Study of Visualization Methods
Wen Luo, Kazushi Numata, Manabu Morimoto, Akito Nozaki, Yasuhiko
Nagano, Kazuya Sugimori, and Katsuaki Tanaka
AJR 2009;192:165-173
http://www.ajronline.org/cgi/content/abstract/192/1/165
Sonography of Acute Right Lower Quadrant Pain: Importance of Increased
Intraabdominal Fat Echo
Min Woo Lee, Young Jun Kim, Hae Jeong Jeon, Sang Woo Park, Sung Il
Jung, and Jeong Geun Yi
AJR 2009;192:174-179
http://www.ajronline.org/cgi/content/abstract/192/1/174
Detection of Hepatocellular Carcinoma in Patients with Cirrhosis: Added
Value of Coronal Reformations from Isotropic Voxels with 64-MDCT
Daniele Marin, Carlo Catalano, Gianmaria De Filippis, Michele Di
Martino, Antonino Guerrisi, Massimo Rossi, and Roberto Passariello
AJR 2009;192:180-187
http://www.ajronline.org/cgi/content/abstract/192/1/180
Cross-Sectional Imaging of Acute and Chronic Gallbladder Inflammatory
Disease
Ethan A. Smith, Jonathan R. Dillman, Khaled M. Elsayes, Christine O.
Menias, and Ronald O. Bude
AJR 2009;192:188-196
http://www.ajronline.org/cgi/content/abstract/192/1/188
Transabdominal Sonography in Assessment of the Bowel in Adults
Siarhei Kuzmich, David C. Howlett, Allan Andi, Dhiren Shah, and
Tatsiana Kuzmich
AJR 2009;192:197-212
http://www.ajronline.org/cgi/content/abstract/192/1/197
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Genitourinary Imaging
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MDCT of the Ovarian Vein: Normal Anatomy and Pathology
Devrim Karaosmanoglu, Musturay Karcaaltincaba, Deniz Karcaaltincaba,
Deniz Akata, and Mustafa Ozmen
AJR 2009;192:295-299
http://www.ajronline.org/cgi/content/abstract/192/1/295
Adrenal Pheochromocytoma with Surrounding Brown Fat Stimulation
Revathy B. Iyer, Charles C. Guo, and Nancy Perrier
AJR 2009;192:300-301
http://www.ajronline.org/cgi/content/full/192/1/300
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Women's Imaging
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Timed Efficiency of Interpretation of Digital and Film-Screen Screening
Mammograms
Tamara Miner Haygood, Jihong Wang, E. Neely Atkinson, Deanna Lane,
Tanya W. Stephens, Parul Patel, and Gary J. Whitman
AJR 2009;192:216-220
http://www.ajronline.org/cgi/content/abstract/192/1/216
Sonographic Surveillance for the Detection of Contralateral Metachronous
Breast Cancer in an Asian Population
Min Jung Kim, Eun-Kyung Kim, Jin Young Kwak, Byeong-Woo Park, Seung-Il
Kim, Joohyuk Sohn, and Ki Keun Oh
AJR 2009;192:221-228
http://www.ajronline.org/cgi/content/abstract/192/1/221
Frequency and Upgrade Rates of Atypical Ductal Hyperplasia Diagnosed at
Stereotactic Vacuum-Assisted Breast Biopsy: 9-Versus 11-Gauge
Peter R. Eby, Jennifer E. Ochsner, Wendy B. DeMartini, Kimberly H.
Allison, Sue Peacock, and Constance D. Lehman
AJR 2009;192:229-234
http://www.ajronline.org/cgi/content/abstract/192/1/229
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Musculoskeletal Imaging
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Periosteal Chondrosarcoma
Skander Chaabane, Mouna Chelli Bouaziz, Cyrine Drissi, Leila Abid, and
Mohamed Fethi Ladeb
AJR 2009;192:1-6
http://www.ajronline.org/cgi/content/abstract/192/1/W1
MRI of Isolated Distal Fibular Fractures with Widened Medial Clear Space on
Stressed Radiographs: Which Ligaments Are Interrupted?
Yvonne Cheung, Kiley D. Perrich, Jiang Gui, Kenneth J. Koval, and
Douglas W. Goodwin
AJR 2009;192:7-12
http://www.ajronline.org/cgi/content/abstract/192/1/W7
Imaging the Ligaments of the Trapeziometacarpal Joint: MRI Compared with MR
Arthrography in Cadaveric Specimens
Fabiano Nassar Cardoso, Hyun-Jin Kim, Flavio Albertotti, Michael J.
Botte, Donald Resnick, and Christine B. Chung
AJR 2009;192:13-19
http://www.ajronline.org/cgi/content/abstract/192/1/W13
Normal Sonographic Anatomy of the Posterolateral Corner of the Knee
Robert P. Barker, Justin C. Lee, and Jeremiah C. Healy
AJR 2009;192:73-79
http://www.ajronline.org/cgi/content/abstract/192/1/73
Comparison of 3-T MRI and Arthroscopy of Intrinsic Wrist Ligament and TFCC
Tears
Thomas Magee
AJR 2009;192:80-85
http://www.ajronline.org/cgi/content/abstract/192/1/80
3-T MRI of the Shoulder: Is MR Arthrography Necessary?
Thomas Magee
AJR 2009;192:86-92
http://www.ajronline.org/cgi/content/abstract/192/1/86
MRI Appearance of the Pectinofoveal Fold
Donna G. Blankenbaker, Kirkland W. Davis, Arthur A. De Smet, and James
S. Keene
AJR 2009;192:93-95
http://www.ajronline.org/cgi/content/abstract/192/1/93
Diagnostic Utility of T1-Weighted MRI Characteristics in Evaluation of
Osteomyelitis of the Foot
Paul W. Johnson, Mark S. Collins, and Doris E. Wenger
AJR 2009;192:96-100
http://www.ajronline.org/cgi/content/abstract/192/1/96
Knee Dislocation in Overweight Patients
Erno K. Peltola, Jan Lindahl, Harri Hietaranta, and Seppo K. Koskinen
AJR 2009;192:101-106
http://www.ajronline.org/cgi/content/abstract/192/1/101
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Pediatric Imaging
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CT with a Computer-Simulated Dose Reduction Technique for Detection of
Pediatric Nephroureterolithiasis: Comparison of Standard and Reduced
Radiation Doses
Boaz Karmazyn, Donald P. Frush, Kimberly E. Applegate, Charles
Maxfield, Mervyn D. Cohen, and Robert P. Jones
AJR 2009;192:143-149
http://www.ajronline.org/cgi/content/abstract/192/1/143
MDCT with Coronal Reconstruction: Clinical Benefit in Evaluation of
Suspected Acute Appendicitis in Pediatric Patients
Yoo Jin Kim, Jee-Eun Kim, Hyung Sik Kim, and Hee Young Hwang
AJR 2009;192:150-152
http://www.ajronline.org/cgi/content/abstract/192/1/150
Congenital Diaphragmatic Hernia: Predictive Value of MRI Relative
Lung-to-Head Ratio Compared with MRI Fetal Lung Volume and Sonographic
Lung-to-Head Ratio
A. Kristina Kilian, Thomas Schaible, Valeska Hofmann, Joachim Brade,
K. Wolfgang Neff, and Karen A. Busing
AJR 2009;192:153-158
http://www.ajronline.org/cgi/content/abstract/192/1/153
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Vascular and Interventional Radiology
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MDCT Angiography After Open Thoracic Aortic Surgery: Pearls and Pitfalls
Jenny K. Hoang, Santiago Martinez, and Lynne M. Hurwitz
AJR 2009;192:20-27
http://www.ajronline.org/cgi/content/abstract/192/1/W20
CT-Guided Percutaneous Catheter Drainage of Acute Necrotizing Pancreatitis:
Clinical Experience and Observations in Patients with Sterile and Infected
Necrosis
Koenraad J. Mortele, Jeffrey Girshman, Denis Szejnfeld, Stanley W.
Ashley, Sukru M. Erturk, Peter A. Banks, and Stuart G. Silverman
AJR 2009;192:110-116
http://www.ajronline.org/cgi/content/abstract/192/1/110
Diagnostic Accuracy of Intraarterial and IV MR Angiography for the
Detection of Stenoses of the Infrainguinal Arteries
Florian Poschenrieder, Okka W. Hamer, Thomas Herold, Thomas
Schleicher, Ingitha Borisch, Stefan Feuerbach, and Niels Zorger
AJR 2009;192:117-121
http://www.ajronline.org/cgi/content/abstract/192/1/117
Evaluation of Patients with Esophageal Varices After Endoscopic Injection
Sclerotherapy Using Multiplanar Reconstruction MDCT Images
Hideaki Kodama, Hiroshi Aikata, Shintaro Takaki, Shoichi Takahashi,
Naoyuki Toyota, Katsuhide Ito, and Kazuaki Chayama
AJR 2009;192:122-130
http://www.ajronline.org/cgi/content/abstract/192/1/122
Predictive Value of Percutaneous Imaging-Guided Biopsy of Peritoneal and
Omental Masses: Results in 111 Patients
Frederico F. Souza, Koenraad J. Mortele, Edmund S. Cibas, Sukru M.
Erturk, and Stuart G. Silverman
AJR 2009;192:131-136
http://www.ajronline.org/cgi/content/abstract/192/1/131
CT-Guided Radiofrequency Ablation in the Treatment of Recurrent Rectal
Cancer
Giuseppe Belfiore, Enrico Tedeschi, Francesco Michele Ronza, Maria
Paola Belfiore, Ettore Borsi, Giovanni Pietro Ianniello, and Antonio
Rotondo
AJR 2009;192:137-141
http://www.ajronline.org/cgi/content/abstract/192/1/137
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Letter
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Intermetatarsal Fat Pad Sign: Radiographic Aid to Diagnosis of Occult
Tarsometatarsal Joint Injuries
Vincent Timpone, Michael Tall, and Andrew Puckett
AJR 2009;192:36-37
http://www.ajronline.org/cgi/content/full/192/1/W36
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Book Reviews
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Imaging of the Chest, vols. 1 and II
Howard I. Jolles
AJR 2009;192:38
http://www.ajronline.org/cgi/content/full/192/1/W38
Keats & Kahn's Roentgen Atlas of Skeletal Maturation
Lane F. Donnelly
AJR 2009;192:39
http://www.ajronline.org/cgi/content/full/192/1/W39
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Nuclear Medicine and Molecular Imaging
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Quantitative Molecular Imaging of Viral Therapy for Pancreatic Cancer Using
an Engineered Measles Virus Expressing the Sodium-Iodide Symporter Reporter
Gene
Stephanie K. Carlson, Kelly L. Classic, Elizabeth M. Hadac, David
Dingli, Claire E. Bender, Bradley J. Kemp, and Stephen J. Russell
AJR 2009;192:279-287
http://www.ajronline.org/cgi/content/abstract/192/1/279
Spectrum of 18F-FDG PET/CT Findings in Oncology-Related Recurrent Laryngeal
Nerve Palsy
Maria Komissarova, Ka Kit Wong, Morand Piert, Suresh K. Mukherji, and
Lorraine M. Fig
AJR 2009;192:288-294
http://www.ajronline.org/cgi/content/abstract/192/1/288
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Neuroradiology/Head and Neck Imaging
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Advances in Pediatric Neuroradiology: Highlights of the Recent Medical
Literature
James M. Provenzale
AJR 2009;192:19-25
http://www.ajronline.org/cgi/content/abstract/192/1/19
Evaluation of the Pediatric Craniocervical Junction on MDCT
John Christopher Bertozzi, Carlos Andres Rojas, and Carlos Rodrigo
Martinez
AJR 2009;192:26-31
http://www.ajronline.org/cgi/content/abstract/192/1/26
Spectrum of Choroid Plexus Lesions in Children
Ramin M. Naeini, Jeong Hyun Yoo, and Jill V. Hunter
AJR 2009;192:32-40
http://www.ajronline.org/cgi/content/abstract/192/1/32
Imaging Findings in Neonatal Hypoxia: A Practical Review
E. Ralph Heinz and James M. Provenzale
AJR 2009;192:41-47
http://www.ajronline.org/cgi/content/abstract/192/1/41
Brain and Bone Abnormalities of Thanatophoric Dwarfism
Elka Miller, Susan Blaser, Patrick Shannon, and Elysa Widjaja
AJR 2009;192:48-51
http://www.ajronline.org/cgi/content/abstract/192/1/48
Diagnostic Determinants of Craniocervical Distraction Injury in Adults
Wilbur Chang, Melvin T. Alexander, and Stuart E. Mirvis
AJR 2009;192:52-58
http://www.ajronline.org/cgi/content/abstract/192/1/52
Correlation of Neurodevelopmental Features and MRI Findings in Infantile
Krabbe's Disease
James M. Provenzale, Srinivas Peddi, Joanne Kurtzberg, Michele D. Poe,
Srinivasan Mukundan, and Maria Escolar
AJR 2009;192:59-65
http://www.ajronline.org/cgi/content/abstract/192/1/59
Performance of Preoperative Sonographic Staging of Papillary Thyroid
Carcinoma Based on the Sixth Edition of the AJCC/UICC TNM Classification
System
Jeong Seon Park, Kyu-Ri Son, Dong Gyu Na, Eunhee Kim, and Sungjun Kim
AJR 2009;192:66-72
http://www.ajronline.org/cgi/content/abstract/192/1/66
Articles from Neurology
Link to journal online
Callen, D J.A. ; Shroff, M M. ; Branson, H M. ; Li, D K. et al
Role of MRI in the differentiation of ADEM from MS in children
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 26 November 2008
Abstract
Background: Acute disseminated encephalomyelitis (ADEM) is typically a monophasic demyelinating disorder. However, a clinical presentation consistent with ADEM can also be the first manifestation of multiple sclerosis (MS), particularly in children. Quantitative analyses of MRI images from children with monophasic ADEM have yet to be compared with those from children with MS, and MRI criteria capable of distinguishing ADEM from MS at onset have yet to be derived.Methods: A retrospective analysis of MRI scans obtained at first attack from 28 children subsequently diagnosed with MS and 20 children with ADEM was performed. T2/fluid-attenuated inversion recovery hyperintense lesions were quantified and categorized according to location, description, and size. T1-weighted images before and after administration of gadolinium were evaluated for the presence of black holes and for gadolinium enhancement. Mean lesion counts and qualitative features were compared between groups and analyzed to create a proposed diagnostic model.Results: Total lesion number did not differentiate ADEM from MS, but periventricular lesions were more frequent in children with MS. Combined quantitative and qualitative analyses led to the following criteria to distinguish MS from ADEM: any two of 1) absence of a diffuse bilateral lesion pattern, 2) presence of black holes, and 3) presence of two or more periventricular lesions. Using these criteria, MS patients at first attack could be distinguished from monophasic ADEM patients with an 81% sensitivity and a 95% specificity.Conclusions: MRI diagnostic criteria are proposed that may be useful in differentiating children experiencing the first attack of multiple sclerosis from those with monophasic acute disseminated encephalomyelitis.GLOSSARY: ADEM = acute disseminated encephalomyelitis; CIS = clinically isolated syndrome; FLAIR = fluid-attenuated inversion recovery; KIDMUS CC = lesions perpendicular to the long axis of the corpus callosum; KIDMUS discrete = sole presence of well-defined lesions; MS = multiple sclerosis; NA = not applicable; NPV = negative predictive value; ON = optic neuritis; OR = odds ratio; PPV = positive predictive value; RRMS = relapsing-remitting multiple sclerosis; TM = transverse myelitis.
Callen, D J.A. ; Shroff, M M. ; Branson, H M. ; Lotze, T et al
MRI in the diagnosis of pediatric multiple sclerosis
Status
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 26 November 2008
Abstract
Background: MRI diagnostic criteria have not yet been adopted for pediatric multiple sclerosis (MS). MRI plays a pivotal role in supporting the diagnosis of MS in adults. We sought to quantitatively define the MRI features of pediatric MS, to determine features that distinguish MS from nondemyelinating relapsing childhood neurologic disorders, and to propose MRI criteria for lesion dissemination in space in children with MS.Methods: A retrospective analysis of MRI scans from 38 children with clinically definite MS and 45 children with nondemyelinating diseases with relapsing neurologic deficits (migraine, systemic lupus erythematosus) was performed. For each scan, T2/FLAIR hyperintense lesions were quantified and categorized according to location and size. Mean lesion counts in specific locations were compared between groups to derive diagnostic criteria. Validation of the proposed criteria was performed using MRI scans from a second independent MS cohort (n = 21).Results: MRI lesion location and size categories differed between children with MS and nondemyelinating controls with a medium to large effect size for most variables. The presence of at least two of the following-five or more lesions, two or more periventricular lesions, or one brainstem lesion-distinguished MS from other nondemyelinating disease controls with 85% sensitivity and 98% specificity.Conclusions: We propose modifications to the currently established McDonald MRI criteria for lesion dissemination in space that will enhance the diagnostic accuracy of these criteria for multiple sclerosis in children.GLOSSARY: ADEM = acute disseminated encephalomyelitis; CDMS = clinically definite MS; MS = multiple sclerosis; OND = other non-demyelinating neurologic diseases; SLE = systemic lupus erythematosus.
Liguori, M ; Mazzei, R P; Ungaro, C ; Simone, I L et al
CONVENTIONAL MRI AND NOTCH3 GENE SCREENING IN SPORADIC CADASIL
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 3 December 2008
Okuda, D T. ; Mowry, E M. ; Beheshtian, A ; Waubant, E et al
Incidental MRI anomalies suggestive of multiple sclerosis: The radiologically isolated syndrome
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 10 December 2008
Abstract
Background: The discovery and broad application of MRI in medicine has led to an increased awareness in the number of patients with incidental white matter pathology in the CNS. Routinely encountered in clinical practice, the natural history or evolution of such individuals with respect to their risk of developing multiple sclerosis (MS) is unclear.Objective: To investigate the natural history of patients who exhibit incidental imaging findings highly suggestive of MS pathology.Methods: Detailed clinical and radiologic data were obtained from asymptomatic patients with MRI anomalies suggestive of MS.Results: The cohort consisted of 41 female and 3 male subjects (median age = 38.5, range: 16.2-67.1). Clinical evaluations were performed in 44 patients at the time of initial imaging; longitudinal clinical follow-up occurred for 30 patients, and longitudinal MRI data were acquired for 41 patients. Neurologic examination at the time of the initial MRI scans was normal in nearly all cases. While radiologic progression was identified in 59% of cases, only 10 patients converted to either clinically isolated syndrome or definite MS. The presence of contrast-enhancing lesions on the initial MRI was predictive of dissemination in time on repeat imaging of the brain (hazard ratio [HR] = 3.4, 95% confidence interval [1.3, 8.7], p = 0.01).Conclusion: Individuals with MRI anomalies highly suggestive of demyelinating pathology, not better accounted for by another disease process, are very likely to experience subsequent radiologic or clinical events related to multiple sclerosis. Additional studies will be necessary to fully define this risk.
Daumer, M P; Neuhaus, A M; Morrissey, S ; Hintzen, R ; Ebers, G C.
MRI as an outcome in multiple sclerosis clinical trials.
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 10 December 2008
Abstract
Introduction: T2-weighted and gadolinium enhanced T1-weighted MRI scans measure plaque burden and breakdown of the blood-brain barrier, respectively, in multiple sclerosis (MS) lesions. These have become widely used outcome measures for monitoring disease activity in clinical trials and clinical practice. However, their use as surrogates or biomarkers for disability and relapses, key clinical outcome measures, has remained incompletely validated.Methods: In a clinical trial database comprised of 31 relapsing-remitting and secondary progressive MS trial placebo groups, we assessed relationships between 1) T2 lesion load (TLL) change and disability change and 2) gadolinium enhancement of MS lesions and on-study relapses with univariate and multivariate analyses.Results: In relapsing-remitting MS, TLL change (n = 223) made no independent contribution to predicting change in disability from baseline to trials' end. Similarly, inclusion of gadolinium enhancing lesions (n = 170) into multivariate models did not independently contribute to the predictive value for on-trial relapses. In secondary progressive MS, a small effect of TLL was found for disability change (n = 355) but in multivariate analysis this accounted for less than 5% of the variance in end-of-trial disability. Results were replicated in independent datasets, more than doubling effective sample sizes.Conclusions: MRI measures widely used in trials of relapsing-remitting and progressive multiple sclerosis add little if anything independently to the clinically relevant relapse and disability outcomes. These results reemphasize the importance of validating potential surrogate markers against clinical measures and highlight the need for better MRI markers of disease activity and progression
Mlynash, M ; Olivot, J H.; Tong, D C. et al
Yield of combined perfusion and diffusion MR imaging in hemispheric TIA
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 17 December 2008
Abstract
Objective: Transient ischemic attacks (TIA) predict future stroke. However, there are no sensitive and specific diagnostic criteria for TIA and interobserver agreement regarding the diagnosis is poor. Diffusion-weighted MRI (DWI) demonstrates acute ischemic lesions in approximately 30% of TIA patients; the yield of perfusion-weighted MRI (PWI) is unclear.Methods: We prospectively performed both DWI and PWI within 48 hours of symptom onset in consecutive patients admitted with suspected hemispheric TIAs of ....
Fellgiebel, A ; Keller, I ; Marin, D; Muller, M J. et al
Diagnostic utility of different MRI and MR angiography measures in Fabry disease
Abstract
Background: Neurologic hallmarks of Fabry disease (FD) include small fiber neuropathy as well as cerebral micro- and macroangiopathy with premature stroke. Cranial MRI shows progressive white matter lesions (WML) at an early age, increased signal intensity in the pulvinar, and tortuosity and dilatation of the larger vessels. To unravel the most promising imaging tool for the detection of CNS involvement in FD we compared the diagnostic utility of the different MR imaging findings.Methods: Twenty-five clinically affected patients with FD (age 36.5 +/- 11.0) and 20 age-matched controls were investigated by structural MRI, MR angiography, and diffusion tensor imaging (DTI). Individual WML volumes, global mean diffusivity (MD), and mean cerebral artery diameters were determined.Results: Using receiver operating characteristic analyses, enlarged diameters of the following cerebral arteries significantly separated patients with FD from controls: middle cerebral artery: area under curve (AUC) = 0.75, p = 0.005; posterior cerebral artery: AUC = 0.69, p = 0.041; carotid artery: 0.69, p = 0.041; basilar artery: AUC = 0.96, p <>
Okello, A ; Edison, P ; Archer, H A. ; Turkheimer, F E. et al
Microglial activation and amyloid deposition in mild cognitive impairment: A PET study
Neurology. 72(1):56-62, January 6, 2009.
Abstract
Background: Activated microglia may play a role in the pathogenesis of Alzheimer disease (AD) as they cluster around beta-amyloid (A[beta]) plaques. They are, therefore, a potential therapeutic target in both AD and its prodrome amnestic mild cognitive impairment (MCI).Objective: To characterize in vivo with 11C-(R)-PK11195 and 11C-PIB PET the distribution of microglial activation and amyloid deposition in patients with amnestic MCI.Methods: Fourteen subjects with MCI had 11C-(R)-PK11195 and 11C-PIB PET with psychometric tests.Results: Seven out of 14 (50%) patients with MCI had increased cortical 11C-PIB retention (p <>
Callen, D J.A. ; Shroff, M M. ; Branson, H M. ; Li, D K. et al
Role of MRI in the differentiation of ADEM from MS in children
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 26 November 2008
Abstract
Background: Acute disseminated encephalomyelitis (ADEM) is typically a monophasic demyelinating disorder. However, a clinical presentation consistent with ADEM can also be the first manifestation of multiple sclerosis (MS), particularly in children. Quantitative analyses of MRI images from children with monophasic ADEM have yet to be compared with those from children with MS, and MRI criteria capable of distinguishing ADEM from MS at onset have yet to be derived.Methods: A retrospective analysis of MRI scans obtained at first attack from 28 children subsequently diagnosed with MS and 20 children with ADEM was performed. T2/fluid-attenuated inversion recovery hyperintense lesions were quantified and categorized according to location, description, and size. T1-weighted images before and after administration of gadolinium were evaluated for the presence of black holes and for gadolinium enhancement. Mean lesion counts and qualitative features were compared between groups and analyzed to create a proposed diagnostic model.Results: Total lesion number did not differentiate ADEM from MS, but periventricular lesions were more frequent in children with MS. Combined quantitative and qualitative analyses led to the following criteria to distinguish MS from ADEM: any two of 1) absence of a diffuse bilateral lesion pattern, 2) presence of black holes, and 3) presence of two or more periventricular lesions. Using these criteria, MS patients at first attack could be distinguished from monophasic ADEM patients with an 81% sensitivity and a 95% specificity.Conclusions: MRI diagnostic criteria are proposed that may be useful in differentiating children experiencing the first attack of multiple sclerosis from those with monophasic acute disseminated encephalomyelitis.GLOSSARY: ADEM = acute disseminated encephalomyelitis; CIS = clinically isolated syndrome; FLAIR = fluid-attenuated inversion recovery; KIDMUS CC = lesions perpendicular to the long axis of the corpus callosum; KIDMUS discrete = sole presence of well-defined lesions; MS = multiple sclerosis; NA = not applicable; NPV = negative predictive value; ON = optic neuritis; OR = odds ratio; PPV = positive predictive value; RRMS = relapsing-remitting multiple sclerosis; TM = transverse myelitis.
Callen, D J.A. ; Shroff, M M. ; Branson, H M. ; Lotze, T et al
MRI in the diagnosis of pediatric multiple sclerosis
Status
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 26 November 2008
Abstract
Background: MRI diagnostic criteria have not yet been adopted for pediatric multiple sclerosis (MS). MRI plays a pivotal role in supporting the diagnosis of MS in adults. We sought to quantitatively define the MRI features of pediatric MS, to determine features that distinguish MS from nondemyelinating relapsing childhood neurologic disorders, and to propose MRI criteria for lesion dissemination in space in children with MS.Methods: A retrospective analysis of MRI scans from 38 children with clinically definite MS and 45 children with nondemyelinating diseases with relapsing neurologic deficits (migraine, systemic lupus erythematosus) was performed. For each scan, T2/FLAIR hyperintense lesions were quantified and categorized according to location and size. Mean lesion counts in specific locations were compared between groups to derive diagnostic criteria. Validation of the proposed criteria was performed using MRI scans from a second independent MS cohort (n = 21).Results: MRI lesion location and size categories differed between children with MS and nondemyelinating controls with a medium to large effect size for most variables. The presence of at least two of the following-five or more lesions, two or more periventricular lesions, or one brainstem lesion-distinguished MS from other nondemyelinating disease controls with 85% sensitivity and 98% specificity.Conclusions: We propose modifications to the currently established McDonald MRI criteria for lesion dissemination in space that will enhance the diagnostic accuracy of these criteria for multiple sclerosis in children.GLOSSARY: ADEM = acute disseminated encephalomyelitis; CDMS = clinically definite MS; MS = multiple sclerosis; OND = other non-demyelinating neurologic diseases; SLE = systemic lupus erythematosus.
Liguori, M ; Mazzei, R P; Ungaro, C ; Simone, I L et al
CONVENTIONAL MRI AND NOTCH3 GENE SCREENING IN SPORADIC CADASIL
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 3 December 2008
Okuda, D T. ; Mowry, E M. ; Beheshtian, A ; Waubant, E et al
Incidental MRI anomalies suggestive of multiple sclerosis: The radiologically isolated syndrome
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 10 December 2008
Abstract
Background: The discovery and broad application of MRI in medicine has led to an increased awareness in the number of patients with incidental white matter pathology in the CNS. Routinely encountered in clinical practice, the natural history or evolution of such individuals with respect to their risk of developing multiple sclerosis (MS) is unclear.Objective: To investigate the natural history of patients who exhibit incidental imaging findings highly suggestive of MS pathology.Methods: Detailed clinical and radiologic data were obtained from asymptomatic patients with MRI anomalies suggestive of MS.Results: The cohort consisted of 41 female and 3 male subjects (median age = 38.5, range: 16.2-67.1). Clinical evaluations were performed in 44 patients at the time of initial imaging; longitudinal clinical follow-up occurred for 30 patients, and longitudinal MRI data were acquired for 41 patients. Neurologic examination at the time of the initial MRI scans was normal in nearly all cases. While radiologic progression was identified in 59% of cases, only 10 patients converted to either clinically isolated syndrome or definite MS. The presence of contrast-enhancing lesions on the initial MRI was predictive of dissemination in time on repeat imaging of the brain (hazard ratio [HR] = 3.4, 95% confidence interval [1.3, 8.7], p = 0.01).Conclusion: Individuals with MRI anomalies highly suggestive of demyelinating pathology, not better accounted for by another disease process, are very likely to experience subsequent radiologic or clinical events related to multiple sclerosis. Additional studies will be necessary to fully define this risk.
Daumer, M P; Neuhaus, A M; Morrissey, S ; Hintzen, R ; Ebers, G C.
MRI as an outcome in multiple sclerosis clinical trials.
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 10 December 2008
Abstract
Introduction: T2-weighted and gadolinium enhanced T1-weighted MRI scans measure plaque burden and breakdown of the blood-brain barrier, respectively, in multiple sclerosis (MS) lesions. These have become widely used outcome measures for monitoring disease activity in clinical trials and clinical practice. However, their use as surrogates or biomarkers for disability and relapses, key clinical outcome measures, has remained incompletely validated.Methods: In a clinical trial database comprised of 31 relapsing-remitting and secondary progressive MS trial placebo groups, we assessed relationships between 1) T2 lesion load (TLL) change and disability change and 2) gadolinium enhancement of MS lesions and on-study relapses with univariate and multivariate analyses.Results: In relapsing-remitting MS, TLL change (n = 223) made no independent contribution to predicting change in disability from baseline to trials' end. Similarly, inclusion of gadolinium enhancing lesions (n = 170) into multivariate models did not independently contribute to the predictive value for on-trial relapses. In secondary progressive MS, a small effect of TLL was found for disability change (n = 355) but in multivariate analysis this accounted for less than 5% of the variance in end-of-trial disability. Results were replicated in independent datasets, more than doubling effective sample sizes.Conclusions: MRI measures widely used in trials of relapsing-remitting and progressive multiple sclerosis add little if anything independently to the clinically relevant relapse and disability outcomes. These results reemphasize the importance of validating potential surrogate markers against clinical measures and highlight the need for better MRI markers of disease activity and progression
Mlynash, M ; Olivot, J H.; Tong, D C. et al
Yield of combined perfusion and diffusion MR imaging in hemispheric TIA
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 17 December 2008
Abstract
Objective: Transient ischemic attacks (TIA) predict future stroke. However, there are no sensitive and specific diagnostic criteria for TIA and interobserver agreement regarding the diagnosis is poor. Diffusion-weighted MRI (DWI) demonstrates acute ischemic lesions in approximately 30% of TIA patients; the yield of perfusion-weighted MRI (PWI) is unclear.Methods: We prospectively performed both DWI and PWI within 48 hours of symptom onset in consecutive patients admitted with suspected hemispheric TIAs of ....
Fellgiebel, A ; Keller, I ; Marin, D; Muller, M J. et al
Diagnostic utility of different MRI and MR angiography measures in Fabry disease
Abstract
Background: Neurologic hallmarks of Fabry disease (FD) include small fiber neuropathy as well as cerebral micro- and macroangiopathy with premature stroke. Cranial MRI shows progressive white matter lesions (WML) at an early age, increased signal intensity in the pulvinar, and tortuosity and dilatation of the larger vessels. To unravel the most promising imaging tool for the detection of CNS involvement in FD we compared the diagnostic utility of the different MR imaging findings.Methods: Twenty-five clinically affected patients with FD (age 36.5 +/- 11.0) and 20 age-matched controls were investigated by structural MRI, MR angiography, and diffusion tensor imaging (DTI). Individual WML volumes, global mean diffusivity (MD), and mean cerebral artery diameters were determined.Results: Using receiver operating characteristic analyses, enlarged diameters of the following cerebral arteries significantly separated patients with FD from controls: middle cerebral artery: area under curve (AUC) = 0.75, p = 0.005; posterior cerebral artery: AUC = 0.69, p = 0.041; carotid artery: 0.69, p = 0.041; basilar artery: AUC = 0.96, p <>
Okello, A ; Edison, P ; Archer, H A. ; Turkheimer, F E. et al
Microglial activation and amyloid deposition in mild cognitive impairment: A PET study
Neurology. 72(1):56-62, January 6, 2009.
Abstract
Background: Activated microglia may play a role in the pathogenesis of Alzheimer disease (AD) as they cluster around beta-amyloid (A[beta]) plaques. They are, therefore, a potential therapeutic target in both AD and its prodrome amnestic mild cognitive impairment (MCI).Objective: To characterize in vivo with 11C-(R)-PK11195 and 11C-PIB PET the distribution of microglial activation and amyloid deposition in patients with amnestic MCI.Methods: Fourteen subjects with MCI had 11C-(R)-PK11195 and 11C-PIB PET with psychometric tests.Results: Seven out of 14 (50%) patients with MCI had increased cortical 11C-PIB retention (p <>
Articles from Spine
Link to journal online
Dickx, Nele ; Cagnie, Barbara ; Achten, Erik; Vandemaele, Pieter et al
Changes in Lumbar Muscle Activity Because of Induced Muscle Pain Evaluated by Muscle Functional Magnetic Resonance Imaging.
Spine. 33(26):E983-E989, December 15, 2008.
Abstract
Study Design. Experimental study of changes in muscle recruitment during trunk extension exercise at 40% of the repetition maximum, because of induced muscle pain.Objective. To investigate the effect of lumbar muscle pain on muscle activity of the trunk muscles using muscle functional magnetic resonance imaging.Summary of Background Data. Changed muscle recruitment in patients has an important impact on the etiology and recurrence of low back pain. The mechanisms of these changes in muscle activity are still poorly understood. An experimental study investigating the cause-effect relationship of muscle pain on muscle recruitment patterns can help to clarify these mechanisms.Methods. In 15 healthy subjects, the muscle activity of the lumbar multifidus, lumbar erector spinae, and psoas muscles was investigated with muscle functional magnetic resonance imaging. Measurements at rest and after trunk extension exercise at 40% of repetition maximum were performed without and with induced pain.Results. The lumbar multifidus and lumbar erector spinae were significantly active during the trunk extension exercise, whereas the psoas showed no significant activity. The activity of the lumbar multifidus, lumbar erector spinae, and psoas muscles, was reduced bilaterally and multilevel during the exercise with unilateral low back muscle pain.Conclusion. These data demonstrate that unilateral muscle pain can cause hypoactivity of muscles during trunk extension at 40% of the repetition maximum. The changes were not limited to the side and level of pain. Moreover, the inhibition was not limited to the multifidus muscle; also the lumbar erector spinae and psoas muscles showed decreased activity during the pain condition. Further research has to assess possible compensation mechanisms for this reduced activity in other muscles.
Dickx, Nele ; Cagnie, Barbara ; Achten, Erik; Vandemaele, Pieter et al
Changes in Lumbar Muscle Activity Because of Induced Muscle Pain Evaluated by Muscle Functional Magnetic Resonance Imaging.
Spine. 33(26):E983-E989, December 15, 2008.
Abstract
Study Design. Experimental study of changes in muscle recruitment during trunk extension exercise at 40% of the repetition maximum, because of induced muscle pain.Objective. To investigate the effect of lumbar muscle pain on muscle activity of the trunk muscles using muscle functional magnetic resonance imaging.Summary of Background Data. Changed muscle recruitment in patients has an important impact on the etiology and recurrence of low back pain. The mechanisms of these changes in muscle activity are still poorly understood. An experimental study investigating the cause-effect relationship of muscle pain on muscle recruitment patterns can help to clarify these mechanisms.Methods. In 15 healthy subjects, the muscle activity of the lumbar multifidus, lumbar erector spinae, and psoas muscles was investigated with muscle functional magnetic resonance imaging. Measurements at rest and after trunk extension exercise at 40% of repetition maximum were performed without and with induced pain.Results. The lumbar multifidus and lumbar erector spinae were significantly active during the trunk extension exercise, whereas the psoas showed no significant activity. The activity of the lumbar multifidus, lumbar erector spinae, and psoas muscles, was reduced bilaterally and multilevel during the exercise with unilateral low back muscle pain.Conclusion. These data demonstrate that unilateral muscle pain can cause hypoactivity of muscles during trunk extension at 40% of the repetition maximum. The changes were not limited to the side and level of pain. Moreover, the inhibition was not limited to the multifidus muscle; also the lumbar erector spinae and psoas muscles showed decreased activity during the pain condition. Further research has to assess possible compensation mechanisms for this reduced activity in other muscles.
Articles from Circulation
Link to journal online
WRITING COMMITTEE MEMBERS; Douglas, Pamela S. , Chair; Hendel, Robert C. Co-Chair; Cummings, Jennifer E. et al,ACCF/ACR/AHA/ASE/ASNC/HRS/NASCI/RSNA/SAIP/SCAI/SCCT/SCMR 2008 Health Policy Statement on Structured Reporting in Cardiovascular Imaging
Publish Ahead of Print, published online before print, 8 December 2008
WRITING COMMITTEE MEMBERS; Hendel, Robert C. , Chair; Budoff, Matthew J. et al
ACC/AHA/ACR/ASE/ASNC/HRS/NASCI/RSNA/SAIP/SCAI/SCCT/SCMR/SIR 2008 Key Data Elements and Definitions for Cardiac Imaging: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Cardiac Imaging)
Publish Ahead of Print, published online before print, 8 December 2008
Nicholls, Stephen J.; Tuzcu, E Murat ; Brennan, Danielle M. et al
Cholesteryl Ester Transfer Protein Inhibition, High-Density Lipoprotein Raising, and Progression of Coronary Atherosclerosis: Insights From ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
118(24):2506-2514, December 9, 2008.
Abstract
Background-: Despite favorable effects on high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol, the cholesteryl ester transfer protein inhibitor torcetrapib failed to slow atherosclerosis progression and increased mortality. We investigated the relationship between lipid changes and progression of coronary atherosclerosis.Methods and Results-: Intravascular ultrasound was performed at baseline and follow-up in 910 participants randomized to torcetrapib/atorvastatin or atorvastatin monotherapy. The relationship between changes in lipoprotein levels and the primary intravascular ultrasound end point, change in percent atheroma volume, was investigated. Compared with atorvastatin monotherapy, torcetrapib raised HDL-C by 61%, lowered low-density lipoprotein cholesterol by 20%, raised serum sodium (0.44+/-0.14 mmol/L, P=0.02), and lowered serum potassium (0.11+/-0.02 mmol/L, P<0.0001). r="-0.17," p="0.002)." p="0.001)." p="0.01)." p="0.001).Conclusions-:">
Josephs, Shellie C. MD, Chair; Rowley, Howard A. MD; Rubin, Geoffrey D. MD; for Writing Group 3
Atherosclerotic Peripheral Vascular Disease Symposium II: Vascular Magnetic Resonance and Computed Tomographic Imaging.[Abstract]
118(25):2837-2844, December 16/23, 2008.
WRITING COMMITTEE MEMBERS; Douglas, Pamela S. , Chair; Hendel, Robert C. Co-Chair; Cummings, Jennifer E. et al,ACCF/ACR/AHA/ASE/ASNC/HRS/NASCI/RSNA/SAIP/SCAI/SCCT/SCMR 2008 Health Policy Statement on Structured Reporting in Cardiovascular Imaging
Publish Ahead of Print, published online before print, 8 December 2008
WRITING COMMITTEE MEMBERS; Hendel, Robert C. , Chair; Budoff, Matthew J. et al
ACC/AHA/ACR/ASE/ASNC/HRS/NASCI/RSNA/SAIP/SCAI/SCCT/SCMR/SIR 2008 Key Data Elements and Definitions for Cardiac Imaging: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Cardiac Imaging)
Publish Ahead of Print, published online before print, 8 December 2008
Nicholls, Stephen J.; Tuzcu, E Murat ; Brennan, Danielle M. et al
Cholesteryl Ester Transfer Protein Inhibition, High-Density Lipoprotein Raising, and Progression of Coronary Atherosclerosis: Insights From ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
118(24):2506-2514, December 9, 2008.
Abstract
Background-: Despite favorable effects on high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol, the cholesteryl ester transfer protein inhibitor torcetrapib failed to slow atherosclerosis progression and increased mortality. We investigated the relationship between lipid changes and progression of coronary atherosclerosis.Methods and Results-: Intravascular ultrasound was performed at baseline and follow-up in 910 participants randomized to torcetrapib/atorvastatin or atorvastatin monotherapy. The relationship between changes in lipoprotein levels and the primary intravascular ultrasound end point, change in percent atheroma volume, was investigated. Compared with atorvastatin monotherapy, torcetrapib raised HDL-C by 61%, lowered low-density lipoprotein cholesterol by 20%, raised serum sodium (0.44+/-0.14 mmol/L, P=0.02), and lowered serum potassium (0.11+/-0.02 mmol/L, P<0.0001). r="-0.17," p="0.002)." p="0.001)." p="0.01)." p="0.001).Conclusions-:">
Josephs, Shellie C. MD, Chair; Rowley, Howard A. MD; Rubin, Geoffrey D. MD; for Writing Group 3
Atherosclerotic Peripheral Vascular Disease Symposium II: Vascular Magnetic Resonance and Computed Tomographic Imaging.[Abstract]
118(25):2837-2844, December 16/23, 2008.
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