Link to journal online
Uchida, Kenzo ; Nakajima, Hideaki ; Yayama, Takafumi ; Kobayashi, Shigeru ; Shimada, Seiichiro et al
High-Resolution Magnetic Resonance Imaging and 18FDG-PET Findings of the Cervical Spinal Cord Before and After Decompressive Surgery in Patients With Compressive Myelopathy.
Status
Publish Ahead of Print, POST AUTHOR CORRECTIONS, 30 April 2009
Abstract
Study Design. Evaluation of cervical spinal cord (CSC) of patients with compressive myelopathy by magnetic resonance imaging (MRI) and high-resolution (18F)fluoro-deoxyglucose (18FDG) positron emission tomography (PET).Objective. To determine changes in morphology, intramedullary signal intensity, and glucose metabolic rate in CSC after decompression, and to assess the utility of 18FDG-PET in evaluation of patients with cervical myelopathy.Summary of Background Data. The significance of CSC enlargement after decompression and signal intensity changes within the cord remain elusive. No data are available on metabolic activity of the compressed CSC. Only a few studies have examined correlation between high-resolution MRI and 18FDG-PET neuroimaging in cervical myelopathy.Methods. We studied 24 patients who underwent cervical decompressive surgery in terms of postoperative neurologic improvement and changes in MRI and 18FDG-PET. Neurologic status was assessed by the Japanese Orthopedic Association scoring system (17-point scale). Signal intensity change in the cord was qualitatively assessed on both T1- and T2-weighted images. The transverse area of the CSC on MRIs and glucose metabolic rate (standardized uptake value [SUV]) from 18FDG-PET were measured digitally.Results. Neurologic improvement correlated with preoperative CSC transverse area at maximal compression (P <>
Pahys, Joshua M. ; Samdani, Amer F. ; Betz, Randal R.
Intraspinal Anomalies in Infantile Idiopathic Scoliosis: Prevalence and Role of Magnetic Resonance Imaging.
Spine. 34(12):E434-E438, May 20, 2009.
Abstract
Study Design. Retrospective case series of magnetic resonance imaging (MRI) findings in patients with presumed infantile idiopathic scoliosis (IIS).Objective. To identify the prevalence of intraspinal anomalies in patients with presumed IIS at a single, large volume institution and further define the role for a screening MRI.Summary of Background Data. Idiopathic scoliosis in patients less than 10 years of age has been shown to carry a higher prevalence of concordant intraspinal anomalies, up to 20%, in juveniles, when compared to the adolescent age group. Few studies exist assessing the prevalence of intraspinal anomalies in the IIS patient population. Dobbs et al (2002) reported a 21.7% prevalence of neural axis abnormalities in 46 patients with presumed IIS across 3 combined spinal deformity clinics and recommended a screening MRI for all IIS patients with a curve >20[degrees].Methods. A retrospective review of the medical records of 54 patients at a single institution with a presumed diagnosis of IIS was performed. All patients satisfied the strict inclusion criteria of: curve >=20[degrees], age <36>20[degrees].(C) 2009 Lippincott Williams & Wilkins, Inc.
Showing posts with label Scoliosis. Show all posts
Showing posts with label Scoliosis. Show all posts
Wednesday, 1 July 2009
Wednesday, 30 April 2008
Spine. 33(9): April 20, 2008
Link to journal and full text
Hay, Douglas FRCS; Izatt, Maree T. BPhty; Adam, Clayton J. PhD; Labrom et al
The Use of Fulcrum Bending Radiographs in Anterior Thoracic Scoliosis Correction: A Consecutive Series of 90 Patients
p. 999-1005
Abstract
Study Design. A prospective, consecutive series of 90 patients receiving fulcrum bending radiographs before endoscopic anterior scoliosis correction.Objective. To assess the effectiveness of fulcrum bending radiographs in predicting correction of the structural curve in anterior scoliosis surgery for a series of 90 consecutive patients.Summary of Background Data. The fulcrum bending radiograph is highly predictive of scoliosis curve correction for posterior instrumented fixation. However, its use has been questioned in relation to anterior scoliosis surgery due to the disc removal in anterior procedures.Methods. Fulcrum bending radiographs were performed before endoscopic anterior scoliosis correction following the protocol of Cheung and Luk. All patients received a single anterior rod and vertebral body screws using a standard compression technique. In all cases, cleared disc spaces were packed with mulched femoral head allograft. Surgical correction was assessed using 6- to 8-week postoperative standing radiographs. Paired t tests and least squares linear regression analysis were used to compare the preoperative major Cobb angle achieved on the fulcrum bending radiograph with the postoperative Cobb angles for each patient.Results. Mean (+/-SD) major curve correction rate was 60.1% +/- 12.4%. Mean instrumented curve correction rate was 63.7% +/- 11.7%. Mean fulcrum flexibility was 60.8% +/- 15.5%. Mean fulcrum bending correction index was 104%. There was no statistically significant difference between the mean fulcrum bending radiograph Cobb angle (20.4 +/- 9[degrees]) and the mean postoperative major Cobb angle for the structural curve (20.5 +/- 7.1[degrees]).Conclusion. The results of this study show that fulcrum bending radiographs are predictive of surgical correction for anterior scoliosis surgery.
Lurie, Jon D.; Tosteson, Anna N. A. ; Tosteson, Tor D. et al
Reliability of Magnetic Resonance Imaging Readings for Lumbar Disc Herniation in the Spine Patient Outcomes Research Trial (SPORT)
p. 991-998
Abstract
Study Design. Assessment of the reliability of standardized magnetic resonance imaging (MRI) interpretations and measurements.Objective. To determine the intra- and inter-reader reliability of MRI parameters relevant to patients with intervertebral disc herniation (IDH), including disc morphology classification, degree of thecal sac compromise, grading of nerve root impingement, and measurements of cross-sectional area of the spinal canal, thecal sac, and disc fragment.Summary of Background Data. MRI is increasingly used to assess patients with sciatica and IDH, but the relationship between specific imaging characteristics and patient outcomes remains uncertain. Although other studies have evaluated the reliability of certain MRI characteristics, comprehensive evaluation of the reliability of readings of herniated disc features on MRI is lacking.Methods. Sixty randomly selected MR images from patients with IDH enrolled in the Spine Patient Outcomes Research Trial were each rated according to defined criteria by 4 independent readers (3 radiologists and 1 orthopedic surgeon). Quantitative measurements were performed separately by 2 other radiologists. A sample of 20 MRIs was re-evaluated by each reader at least 1 month later. Agreement for rating data were assessed with kappa statistics using linear weights. Reliability of the quantitative measurements was assessed using intraclass correlation coefficients (ICCs) and summaries of measurement error.Results. Inter-reader reliability was substantial for disc morphology [overall kappa 0.81 (95% confidence interval (CI): 0.78, 0.85)], moderate for thecal sac compression [overall kappa 0.54 (95% CI: 0.37, 0.68)], and moderate for grading nerve root impingement [overall kappa 0.47 (95% CI: 0.36, 0.56)]. Quantitative measures showed high ICCs of 0.87 to 0.96 for spinal canal and thecal sac cross-sectional areas. Measures of disc fragment area had moderate ICCs of 0.65 to 0.83. Mean absolute differences between measurements ranged from approximately 15% to 20%.Conclusion. Classification of disc morphology showed substantial intra- and inter-reader agreement, whereas thecal sac and nerve root compression showed more moderate reader reliability. Quantitative measures of canal and thecal sac area showed good reliability, whereas measurement of disc fragment area showed more modest reliability.
Hay, Douglas FRCS; Izatt, Maree T. BPhty; Adam, Clayton J. PhD; Labrom et al
The Use of Fulcrum Bending Radiographs in Anterior Thoracic Scoliosis Correction: A Consecutive Series of 90 Patients
p. 999-1005
Abstract
Study Design. A prospective, consecutive series of 90 patients receiving fulcrum bending radiographs before endoscopic anterior scoliosis correction.Objective. To assess the effectiveness of fulcrum bending radiographs in predicting correction of the structural curve in anterior scoliosis surgery for a series of 90 consecutive patients.Summary of Background Data. The fulcrum bending radiograph is highly predictive of scoliosis curve correction for posterior instrumented fixation. However, its use has been questioned in relation to anterior scoliosis surgery due to the disc removal in anterior procedures.Methods. Fulcrum bending radiographs were performed before endoscopic anterior scoliosis correction following the protocol of Cheung and Luk. All patients received a single anterior rod and vertebral body screws using a standard compression technique. In all cases, cleared disc spaces were packed with mulched femoral head allograft. Surgical correction was assessed using 6- to 8-week postoperative standing radiographs. Paired t tests and least squares linear regression analysis were used to compare the preoperative major Cobb angle achieved on the fulcrum bending radiograph with the postoperative Cobb angles for each patient.Results. Mean (+/-SD) major curve correction rate was 60.1% +/- 12.4%. Mean instrumented curve correction rate was 63.7% +/- 11.7%. Mean fulcrum flexibility was 60.8% +/- 15.5%. Mean fulcrum bending correction index was 104%. There was no statistically significant difference between the mean fulcrum bending radiograph Cobb angle (20.4 +/- 9[degrees]) and the mean postoperative major Cobb angle for the structural curve (20.5 +/- 7.1[degrees]).Conclusion. The results of this study show that fulcrum bending radiographs are predictive of surgical correction for anterior scoliosis surgery.
Lurie, Jon D.; Tosteson, Anna N. A. ; Tosteson, Tor D. et al
Reliability of Magnetic Resonance Imaging Readings for Lumbar Disc Herniation in the Spine Patient Outcomes Research Trial (SPORT)
p. 991-998
Abstract
Study Design. Assessment of the reliability of standardized magnetic resonance imaging (MRI) interpretations and measurements.Objective. To determine the intra- and inter-reader reliability of MRI parameters relevant to patients with intervertebral disc herniation (IDH), including disc morphology classification, degree of thecal sac compromise, grading of nerve root impingement, and measurements of cross-sectional area of the spinal canal, thecal sac, and disc fragment.Summary of Background Data. MRI is increasingly used to assess patients with sciatica and IDH, but the relationship between specific imaging characteristics and patient outcomes remains uncertain. Although other studies have evaluated the reliability of certain MRI characteristics, comprehensive evaluation of the reliability of readings of herniated disc features on MRI is lacking.Methods. Sixty randomly selected MR images from patients with IDH enrolled in the Spine Patient Outcomes Research Trial were each rated according to defined criteria by 4 independent readers (3 radiologists and 1 orthopedic surgeon). Quantitative measurements were performed separately by 2 other radiologists. A sample of 20 MRIs was re-evaluated by each reader at least 1 month later. Agreement for rating data were assessed with kappa statistics using linear weights. Reliability of the quantitative measurements was assessed using intraclass correlation coefficients (ICCs) and summaries of measurement error.Results. Inter-reader reliability was substantial for disc morphology [overall kappa 0.81 (95% confidence interval (CI): 0.78, 0.85)], moderate for thecal sac compression [overall kappa 0.54 (95% CI: 0.37, 0.68)], and moderate for grading nerve root impingement [overall kappa 0.47 (95% CI: 0.36, 0.56)]. Quantitative measures showed high ICCs of 0.87 to 0.96 for spinal canal and thecal sac cross-sectional areas. Measures of disc fragment area had moderate ICCs of 0.65 to 0.83. Mean absolute differences between measurements ranged from approximately 15% to 20%.Conclusion. Classification of disc morphology showed substantial intra- and inter-reader agreement, whereas thecal sac and nerve root compression showed more moderate reader reliability. Quantitative measures of canal and thecal sac area showed good reliability, whereas measurement of disc fragment area showed more modest reliability.
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